Research Articles

Research Articles

“Dissecting the copper bioinorganic chemistry of the functional and pathological roles of the prion protein: Relevance in Alzheimer´s disease and cancer”

Posadas, Y.; López-Guerrero, V.E.; Segovia, J.; Perez-Cruz, C.; Quintanar, L. “Dissecting the copper bioinorganic chemistry of the functional and pathological roles of the prion protein: Relevance in Alzheimer´s disease and cancer” Curr.Opin. Chem. Biol. 2022, 66, 102098. https://doi.org/10.1016/j.cbpa.2021.102098

“Dissecting the copper bioinorganic chemistry of the functional and pathological roles of the prion protein: Relevance in Alzheimer´s disease and cancer” Read Post »

Research Articles

“Reversible stereoisomer-specific Cotton effect of the ligand field transitions at a copper(II) binding site of the prion protein”

Rivillas-Acevedo, L.; Grande-Aztatzi, R.; Juaristi, E.; Vela, A.; Quintanar, L. “Reversible stereoisomer-specific Cotton effect of the ligand field transitions at a copper(II) binding site of the prion protein” Eur. J. Inorg Chem. 2022, in press https://doi.org/10.1002/ejic.202100625

“Reversible stereoisomer-specific Cotton effect of the ligand field transitions at a copper(II) binding site of the prion protein” Read Post »

Research Articles

“Structural and electronic analysis of the octarepeat region of prion protein with four Cu2+ by polarizable MD and QM/MM simulations”

Nochebuena, J.; Quintanar, L.; Vela, A.; Cisneros, G. A. “Structural and electronic analysis of the octarepeat region of prion protein with four Cu2+ by polarizable MD and QM/MM simulations” Phys. Chem. Chem. Phys. 2021, 23, 21568.  https://doi.org/10.1039/d1cp03187b

“Structural and electronic analysis of the octarepeat region of prion protein with four Cu2+ by polarizable MD and QM/MM simulations” Read Post »

Research Articles

“Amyloid β perturbs Cu(II) binding to the prion protein in a site-specific manner: Insights into its potential neurotoxic mechanisms”

Posadas, Y.; Parra-Ojeda, L.; Perez-Cruz, C.; Quintanar, L. “Amyloid β perturbs Cu(II) binding to the prion protein in a site-specific manner: Insights into its potential neurotoxic mechanisms” Inorg. Chem. 2021, 60, 12, 8958-8972. https://doi.org/10.1021/acs.inorgchem.1c00846

“Amyloid β perturbs Cu(II) binding to the prion protein in a site-specific manner: Insights into its potential neurotoxic mechanisms” Read Post »

Research Articles

“Thermodynamic stability of human γD-crystallin mutants using alchemical free-energy calculations”

Aguayo-Ortiz, R.; González-Navejas, A.; Palomino-Vizcaino, G.; Rodriguez-Meza, O.; Costas, M.;  Quintanar, L.; Dominguez, L. “Thermodynamic stability of human γD-crystallin mutants using alchemical free-energy calculations” J. Phys. Chem. B 2019, 123, 5671-5677.  https://doi.org/10.1021/acs.jpcb.9b01818

“Thermodynamic stability of human γD-crystallin mutants using alchemical free-energy calculations” Read Post »

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